glycolysis can occur under aerobic or anaerobic conditions


(Image Source: “Anaerobic vs. Aerobic pathways” In aerobic glycolysis, the end product, pyruvate is transferred to mitochondria for the initiation of Citric acid cycle. Anaerobic glycolysis is the transformation of glucose to lactate when limited amounts of oxygen (O 2) are available. Compare the Difference Between Similar Terms. If oxygen is available, then the free energy contained in NADH is further released via reoxidization of the mitochondrial electron chain and results in the release of 30 more mol of ATP per mol of glucose.However, when oxygen is in short supply, this NADH is reoxidized instead by reducing pyruvate to lactate. Anaerobic glycolysis produces (2 lactate + 2 ATP + 2 H2O + 2 H+) from one glucose molecule. New York: McGraw-Hill; 2011. All rights reserved. • Aerobic glycolysis occurs only in eukaryotes while anaerobic glycolysis occurs in both prokaryotes and eukaryotes. Glycolysis & the Oxidation of Pyruvate. In mammals, lactate can be transformed by the liver back into glucose using the Cori cycle. Web. The acid produced by glycolysis lowers the pH both inside cells where lactate is produced as well as outside where protons can diffuse. This process alone generates 2 molecules of ATP. This is clinically significant because oxidation of glucose under aerobic conditions results in 32 mol of ATP per mol of glucose. • Aerobic glycolysis is more efficient than anaerobic glycolysis; hence it produces a large amount of ATP than anaerobic glycolysis. Bender DA, Mayes PA. Chapter 18. Unlike the aerobic glycolysis, anaerobic glycolysis produces lactate, which reduces the pH and inactivates the enzymes. In simple words, glycolysis is a process that coverts glucose into energy. The consequence is lactic acidosis, a life-threatening condition. (adsbygoogle = window.adsbygoogle || []).push({}); Copyright © 2010-2018 Difference Between. This severely limits the amount of ATP formed per mole of glucose oxidized when compared with aerobic glycolysis. The major difference between aerobic and anaerobic glycolysis is the presence or absence of oxygen. Aerobic glycolysis occurs in 2 steps. Since the pH range in which cells can function is quite narrow (pH 7.0–7.6), uncontrolled glycolysis can lead to cell death. • Ultimate end product of anaerobic glycolysis is lactate, which may be harmful to the cell itself, whereas that of aerobic glycolysis is water and carbon dioxide, which are not harmful to cells. It replenishes very quickly over this period and produces 2 ATP molecules per glucose molecule,[3] or about 5% of glucose's energy potential (38 ATP molecules). Glycolysis does not require oxygen and can occur under aerobic and anaerobic conditions. Anaerobic glycolysis is thought to have been the primary means of energy production in earlier organisms before oxygen was at high concentration in the atmosphere and thus would represent a more ancient form of energy production in cells. • Unlike in anaerobic glycolysis, NADH + H+ undergo oxidative phosphorylation in the presence of oxygen in aerobic glycolysis. [1] Anaerobic glycolysis is only an effective means of energy production during short, intense exercise,[1] providing energy for a period ranging from 10 seconds to 2 minutes. Difference Between Catabolism and Anabolism, Difference Between Biodiversity and Species Richness, Difference Between Locomotion and Movement, Difference Between Abduction and Adduction, Difference Between Coronavirus and Cold Symptoms, Difference Between Coronavirus and Influenza, Difference Between Coronavirus and Covid 19, Difference Between Genetic Engineering and Recombinant DNA Technology, Difference Between This and It in English Grammar, Difference Between Sucralose and Aspartame, Difference Between Enantiotopic and Diastereotopic, Difference Between Acanthosis and Acantholysis, Difference Between Granular and Agranular Endoplasmic Reticulum, Difference Between Trophoblast and Inner Cell Mass, Difference Between O Acylation and N Acylation, Difference Between Water Potential and Osmotic Potential. Regardless of whether anaerobic or aerobic, glycolysis produces acid if lactate is the end product of the pathway. Aerobic glycolysis produces pyruvate at the end of glycolysis while anaerobic glycolysis produces lactate. In situations where there is an imbalance of oxygen usage and oxygen delivery, for example in sepsis or heart failure, anaerobic glycolysis occurs and results in lactate accumulation and results in inefficient glucose usage and inadequate ATP production. Therefore, the ultimate products of aerobic glycolysis are 34 ATP molecules, water, and carbon dioxide. In addition to being oxidatively metabolized, many polyhalogenated alkanes are converted by a P450-dependent, one-electron reduction pathway to a free radical intermediate and inorganic halide.

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